BDBM50032463 CHEMBL3353547::US9353075, 19
SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OCCCCC1CCCCC1
InChI Key InChIKey=QEPPAKHKNZHDCV-WCQYABFASA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50032463
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
University Of California
US Patent
University Of California
US Patent
Affinity DataIC50: 20nMpH: 7.4Assay Description:Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University Of California
US Patent
University Of California
US Patent
Affinity DataIC50: 9nMpH: 4.5 T: 2°CAssay Description:NAAA protein preparation (10 ug) was pre-incubated with various concentrations of test compound or vehicle control in 100 mM NaH2PO4, 100 mM Tri Sodi...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
University Of California
US Patent
University Of California
US Patent
Affinity DataIC50: 20nMAssay Description:Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS methodMore data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
University Of California
US Patent
University Of California
US Patent
Affinity DataIC50: 21nMAssay Description:Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS methodMore data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University Of California
US Patent
University Of California
US Patent
Affinity DataIC50: 8nMpH: 4.5Assay Description:The assay was run in Optiplate 96-wells black plates, in a total reaction volume of 200 μL. NAAA protein preparation (4.0 μg) was pre-incub...More data for this Ligand-Target Pair