BDBM50033775 (R)-4-Ethyl-9-fluoro-4-hydroxy-3,13-dioxo-3,4,12,13-tetrahydro-1H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-11-carboxylic acid::CHEMBL353531

SMILES CC[C@]1(O)C(=O)OCc2c1cc1-c3nc4ccc(F)cc4c(C(O)=O)c3Cn1c2=O

InChI Key InChIKey=BXZNPPRHZXWPSN-OAQYLSRUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033775   

TargetDNA topoisomerase 1(Homo sapiens (Human))
Glaxo Research Institute

Curated by ChEMBL
LigandPNGBDBM50033775((R)-4-Ethyl-9-fluoro-4-hydroxy-3,13-dioxo-3,4,12,1...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibitory concentration of the compound against topoisomerase I obtained from calf thymusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed