BDBM50035846 CHEMBL3359912

SMILES CC1(C)[C@@H](O)CC[C@H]1Nc1c(cnn2cccc12)C(N)=O

InChI Key InChIKey=NQMVPZBPGADIQN-NEPJUHHUSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50035846   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50035846(CHEMBL3359912)
Affinity DataIC50:  130nMAssay Description:Inhibition of JAK2 (unknown origin) by caliper assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50035846(CHEMBL3359912)
Affinity DataIC50:  79nMAssay Description:Inhibition of TYK2 (unknown origin) by caliper assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50035846(CHEMBL3359912)
Affinity DataIC50:  16nMAssay Description:Inhibition of JAK3 (unknown origin) by filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50035846(CHEMBL3359912)
Affinity DataIC50:  62nMAssay Description:Inhibition of JAK1 (unknown origin) bycaliper assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed