BDBM50040911 (+)-myo-inositol 1,4,5-trisphosphorothioate::(-)-chiro-inositol 1,4,6-trisphosphorothioate::1,4,5-trisphosphate 5-phosphatase derivatives::Inositol 1,4,5-trisphosphorothioate::L-(1,4,5)PS3::{[2,5-bis({[dioxido(sulfanylidene)--phosphanyl]oxy})-3,4,6-trihydroxycyclohexyl]oxy}(sulfanylidene)phosphonite

SMILES OC1C(O)C(OP([O-])([O-])=S)C(OP([O-])([O-])=S)C(O)C1OP([O-])([O-])=S

InChI Key InChIKey=BZIDQHFQSPKXER-UHFFFAOYSA-H

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50040911   

TargetInositol-trisphosphate 3-kinase C(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50040911((+)-myo-inositol 1,4,5-trisphosphorothioate | (-)-...)
Affinity DataKi:  9.78E+5nMAssay Description:Tested for the ability to inhibit Ins(1,4,5)P 3-phosphataseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType 1 InsP3 receptor isoform S2(Sus scrofa)
Mayo Foundation

Curated by ChEMBL
LigandPNGBDBM50040911((+)-myo-inositol 1,4,5-trisphosphorothioate | (-)-...)
Affinity DataIC50:  78nMpH: 6.8Assay Description:Binding affinity against IP3 receptor in pig cerebellar membranes at a pH of 6.8 using [3H]Ins(1,4,5)P3 as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType 1 InsP3 receptor isoform S2(Sus scrofa)
Mayo Foundation

Curated by ChEMBL
LigandPNGBDBM50040911((+)-myo-inositol 1,4,5-trisphosphorothioate | (-)-...)
Affinity DataIC50:  61nMpH: 7.6Assay Description:Binding affinity against IP3 receptor in pig cerebellar membranes at a pH of 7.6 using [3H]Ins(1,4,5)P3 as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed