BDBM50046560 17-(1,5-Dimethyl-hexyl)-14-(1-hydroxy-ethyl)-4,4,10,13-tetramethyl-2,3,4,5,6,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol::CHEMBL133834

SMILES CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C(C)O)C3=CCC4C(C)(C)[C@@H](O)CC[C@]4(C)C3CC[C@]12C

InChI Key InChIKey=BOQKRCLAJMWJDG-ZHLGQSRNSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50046560   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50046560(17-(1,5-Dimethyl-hexyl)-14-(1-hydroxy-ethyl)-4,4,1...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of HMG-coA Reductase enzyme in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol 14-alpha demethylase(Rattus norvegicus)
Institute

Curated by ChEMBL
LigandPNGBDBM50046560(17-(1,5-Dimethyl-hexyl)-14-(1-hydroxy-ethyl)-4,4,1...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition rat liver microsome cytochrome P450DMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol 14-alpha demethylase(Rattus norvegicus)
Institute

Curated by ChEMBL
LigandPNGBDBM50046560(17-(1,5-Dimethyl-hexyl)-14-(1-hydroxy-ethyl)-4,4,1...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition rat liver microsome cytochrome P450DMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol 14-alpha demethylase(Rattus norvegicus)
Institute

Curated by ChEMBL
LigandPNGBDBM50046560(17-(1,5-Dimethyl-hexyl)-14-(1-hydroxy-ethyl)-4,4,1...)
Affinity DataIC50:  300nMAssay Description:Inhibition rat liver microsome cytochrome P450DMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50046560(17-(1,5-Dimethyl-hexyl)-14-(1-hydroxy-ethyl)-4,4,1...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of HMG-coA Reductase enzyme in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50046560(17-(1,5-Dimethyl-hexyl)-14-(1-hydroxy-ethyl)-4,4,1...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of HMG-coA Reductase enzyme in AR45 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed