BDBM50049146 CHEMBL3315251::US11401286, Example 36

SMILES OC(=O)Cc1ccc(Nc2nc(nc(n2)-c2cccc(Cl)c2)C2CC2)cc1

InChI Key InChIKey=CJQFUKZLNADPJB-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50049146   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049146(CHEMBL3315251 | US11401286, Example 36)
Affinity DataIC50:  237nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049146(CHEMBL3315251 | US11401286, Example 36)
Affinity DataIC50:  1.18E+3nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetIsoform 7 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Tetra Discovery Partners

US Patent
LigandPNGBDBM50049146(CHEMBL3315251 | US11401286, Example 36)
Affinity DataIC50: >1.00E+3nMAssay Description:Assays are performed in 96-well plates in a total volume of 200 μl/well. Compounds are dissolved in dimethylsulfoxide (DMSO) and added to plates...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D7 [S54D](Homo sapiens (Human))
Tetra Discovery Partners

US Patent
LigandPNGBDBM50049146(CHEMBL3315251 | US11401286, Example 36)
Affinity DataIC50: >1.00E+3nMAssay Description:Assays are performed in 96-well plates in a total volume of 200 μl/well. Compounds are dissolved in dimethylsulfoxide (DMSO) and added to plates...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B [S133D](Homo sapiens (Human))
Tetra Discovery Partners

US Patent
LigandPNGBDBM50049146(CHEMBL3315251 | US11401286, Example 36)
Affinity DataIC50: <1.00E+3nMAssay Description:Assays are performed in 96-well plates in a total volume of 200 μl/well. Compounds are dissolved in dimethylsulfoxide (DMSO) and added to plates...More data for this Ligand-Target Pair
In DepthDetails US Patent