BDBM50051394 2-[(R)-2-{2-Cyclopropyl-2-[((2R,6S)-2,6-dimethyl-piperidine-1-carbonyl)-amino]-acetylamino}-3-(2-methyl-1H-indol-3-yl)-propionylamino]-4-methylsulfanyl-butyric acid::CHEMBL307936

SMILES CSCCC(NC(=O)[C@@H](Cc1c(C)[nH]c2ccccc12)NC(=O)C(NC(=O)N1[C@@H](C)CCC[C@H]1C)C1CC1)C(O)=O

InChI Key InChIKey=XUXCOWLSMHJSSY-OTQGITMZSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50051394   

TargetEndothelin-1 receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50051394(2-[(R)-2-{2-Cyclopropyl-2-[((2R,6S)-2,6-dimethyl-p...)
Affinity DataIC50:  3nMAssay Description:Binding affinity towards Endothelin A receptor in human neuroblastoma-derived cell line SK-N-MC membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50051394(2-[(R)-2-{2-Cyclopropyl-2-[((2R,6S)-2,6-dimethyl-p...)
Affinity DataIC50:  1nMAssay Description:Binding affinity towards endothelin A receptor in porcine aortic smooth muscle membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Sus scrofa)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50051394(2-[(R)-2-{2-Cyclopropyl-2-[((2R,6S)-2,6-dimethyl-p...)
Affinity DataIC50:  2.90nMAssay Description:Binding affinity towards endothelin B receptor in porcine cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50051394(2-[(R)-2-{2-Cyclopropyl-2-[((2R,6S)-2,6-dimethyl-p...)
Affinity DataIC50:  4nMAssay Description:Binding affinity towards Endothelin B receptor in human girardi heart cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed