BDBM50054498 (R)-1-((R)-2-Methylamino-3-phenyl-propionyl)-pyrrolidine-2-carboxylic acid ((S)-3-carbamimidoyl-2-hydroxy-cyclohexyl)-amide::CHEMBL423543

SMILES CN[C@H](Cc1ccccc1)C(=O)N1CCC[C@@H]1C(=O)N[C@H]1CCCC(C1O)C(N)=N

InChI Key InChIKey=GIJSEQPSPRTDPP-OLOUCDKRSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50054498   

TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054498((R)-1-((R)-2-Methylamino-3-phenyl-propionyl)-pyrro...)
Affinity DataIC50:  1.52nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054498((R)-1-((R)-2-Methylamino-3-phenyl-propionyl)-pyrro...)
Affinity DataIC50:  0.700nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054498((R)-1-((R)-2-Methylamino-3-phenyl-propionyl)-pyrro...)
Affinity DataIC50: >2.50E+3nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed