BDBM50055017 7,8-Dichloro-5-(4-chloro-phenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol::CHEMBL132955
SMILES OC1(N2CCN=C2c2cc(Cl)c(Cl)cc12)c1ccc(Cl)cc1
InChI Key InChIKey=JOBHARMVZDXCRY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50055017
Affinity DataKi: 1.05nMAssay Description:Displacement of [125I]- RTI-55 from Dopamine transporter expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Displacement of [125I]RTI-55 from human Norepinephrine transporter expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.35E+3nMAssay Description:Displacement of [125I]- RTI-55 from Serotonin transporter expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataIC50: 13.6nMAssay Description:Ability to displace [3H]WIN-35428 from Dopamine Transporter of rat striatal membraneMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of NE uptake in HEK cells expressing human noradrenaline transporter (hNET)More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of dopamine uptake in HEK cells expressing human dopamine transporter (hDAT)More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Ability to displace [3H]-WIN-35,428 from dopamine transporter in rat caudate putamen tissueMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataIC50: 13.6nMAssay Description:Inhibition of [3H]-WIN- 35,428 binding to the dopamine transporter in rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 444nMAssay Description:Inhibition of 5-HT uptake in HEK cells expressing human serotonin transporter (hSERT)More data for this Ligand-Target Pair