BDBM50055341 CHEMBL149502::[3-(1-BENZYL-3-CARBAMOYLMETHYL-2-METHYL-1H-INDOL-5-YLOXY)-PROPYL-]-PHOSPHONIC ACID::[3-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-5-yloxy)-propyl]-phosphonic acid::hnpsPLA2-IIa Inhibitor, 1

SMILES Cc1c(CC(N)=O)c2cc(OCCCP(O)(O)=O)ccc2n1Cc1ccccc1

InChI Key InChIKey=AQEYCNKFBRLUOT-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50055341   

TargetPhospholipase A2(Homo sapiens (Human))
University Of Queensland Brisbane

LigandPNGBDBM50055341(CHEMBL149502 | [3-(1-BENZYL-3-CARBAMOYLMETHYL-2-ME...)
Affinity DataIC50:  60nMAssay Description:Compounds 2a-q were evaluated as inhibitors by using an in vitro colorimetric enzyme assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50055341(CHEMBL149502 | [3-(1-BENZYL-3-CARBAMOYLMETHYL-2-ME...)
Affinity DataIC50:  57nMAssay Description:Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assayMore data for this Ligand-Target Pair
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50055341(CHEMBL149502 | [3-(1-BENZYL-3-CARBAMOYLMETHYL-2-ME...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibitory activity against porcine pancreatic Phospholipase A2More data for this Ligand-Target Pair
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50055341(CHEMBL149502 | [3-(1-BENZYL-3-CARBAMOYLMETHYL-2-ME...)
Affinity DataIC50:  6.70E+4nMAssay Description:Inhibitory activity against human pancreatic Phospholipase A2More data for this Ligand-Target Pair