BDBM50058983 3-(3-Methoxy-benzenesulfonyl)-1-phenyl-imidazolidine-2,4-dione::CHEMBL65936

SMILES COc1cccc(c1)S(=O)(=O)N1C(=O)CN(C1=O)c1ccccc1

InChI Key InChIKey=KDVFGQRTDBJTGS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50058983   

TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058983(3-(3-Methoxy-benzenesulfonyl)-1-phenyl-imidazolidi...)
Affinity DataIC50:  580nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058983(3-(3-Methoxy-benzenesulfonyl)-1-phenyl-imidazolidi...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058983(3-(3-Methoxy-benzenesulfonyl)-1-phenyl-imidazolidi...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibitory activity against human neutrophil cathepsin G.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed