BDBM50062427 9-Fluoro-2,2,4-trimethyl-5-m-tolyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene::CHEMBL320164

SMILES CC1=CC(C)(C)Nc2ccc3-c4cc(F)ccc4OC(c4cccc(C)c4)c3c12

InChI Key InChIKey=RGLLPBRDVGGNJE-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50062427   

TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062427(9-Fluoro-2,2,4-trimethyl-5-m-tolyl-2,5-dihydro-1H-...)
Affinity DataKi:  0.370nMAssay Description:The binding affinity measured using baculovirus-expressed hPR-A in sf21 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062427(9-Fluoro-2,2,4-trimethyl-5-m-tolyl-2,5-dihydro-1H-...)
Affinity DataEC50:  5nMAssay Description:Agonistic activity was measured for modulation of hPR-B (human progesterone receptor) in co-transfected CV-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed