BDBM50065418 3-[3-(4-Benzyl-piperidin-1-yl)-2-fluoro-propyl]-5-[1,2,4]triazol-4-yl-1H-indole::CHEMBL432332

SMILES FC(CN1CCC(Cc2ccccc2)CC1)Cc1c[nH]c2ccc(cc12)-n1cnnc1

InChI Key InChIKey=MNQUDTHIXVJDIS-UHFFFAOYSA-N

Data  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50065418   

Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50065418(3-[3-(4-Benzyl-piperidin-1-yl)-2-fluoro-propyl]-5-...)
Affinity DataEC50:  11nMAssay Description:Agonist induced [35S]-GTP-gammaS, binding in CHO cells expressing 5-HT 1d receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50065418(3-[3-(4-Benzyl-piperidin-1-yl)-2-fluoro-propyl]-5-...)
Affinity DataIC50:  62nMAssay Description:Displacement of specific [3H]-5-HT binding to cloned human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50065418(3-[3-(4-Benzyl-piperidin-1-yl)-2-fluoro-propyl]-5-...)
Affinity DataEC50:  0.900nMAssay Description:Agonist-induced [35S]-GTP-gammaS, binding in CHO cells stably transfected with human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50065418(3-[3-(4-Benzyl-piperidin-1-yl)-2-fluoro-propyl]-5-...)
Affinity DataIC50:  0.950nMAssay Description:Displacement of [3H]-5-HT from human 5-hydroxytryptamine 1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50065418(3-[3-(4-Benzyl-piperidin-1-yl)-2-fluoro-propyl]-5-...)
Affinity DataEC50:  450nMAssay Description:Agonist-induced [35S]-GTP-gammaS, binding in CHO cells stably transfected with human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50065418(3-[3-(4-Benzyl-piperidin-1-yl)-2-fluoro-propyl]-5-...)
Affinity DataIC50:  0.900nMAssay Description:Displacement of specific [3H]-5-HT binding to cloned human 5-hydroxytryptamine 1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed