BDBM50066519 CHEMBL3403102

SMILES Fc1cc(cc(c1)S(=O)(=O)c1sc2ncccc2c1-c1ccccc1F)C#N

InChI Key InChIKey=IQBXHAPVFAJRMV-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50066519   

TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50066519(CHEMBL3403102)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50066519(CHEMBL3403102)
Affinity DataIC50:  1.5nMAssay Description:Negative allosteric modulation of mGlu5 receptor in primary E17 rat embryo neuron assessed as ca2+ level by fluo-4/AM assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed