BDBM50068784 6-(Isothiazol-4-ylmethoxy)-6,9-dihydro-1H-purin-2-ylamine::CHEMBL150324

SMILES NC1=Nc2nc[nH]c2C(N1)OCc1cnsc1

InChI Key InChIKey=VTDHOCRXHWVGPM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50068784   

TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50068784(6-(Isothiazol-4-ylmethoxy)-6,9-dihydro-1H-purin-2-...)
Affinity DataIC50:  70nMAssay Description:O6-Alkylguanine-DNA Alkyltransferase-Inactivating Activity in Raji cells (Concentration of inactivator required to produce 50% reduction in ATPase ac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50068784(6-(Isothiazol-4-ylmethoxy)-6,9-dihydro-1H-purin-2-...)
Affinity DataIC50:  70nMAssay Description:O6-Alkylguanine-DNA Alkyltransferase-Inactivating Activity (Concentration of inactivator required to produce 50% reduction in ATPase activity) More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed