BDBM50072569 (2R,3S)-2-Allyl-N*4*-((S)-1-benzyl-2-oxazol-2-yl-2-oxo-ethyl)-N*1*-hydroxy-3-isobutyl-succinamide::(2S,3R)-2-allyl-N1-hydroxy-3-isobutyl-N4-((S)-1-(oxazol-2-yl)-1-oxo-3-phenylpropan-2-yl)succinamide::CHEMBL430524

SMILES CC(C)C[C@H]([C@H](CC=C)C(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(=O)c1ncco1

InChI Key InChIKey=BZTWELLPCHJZLB-OTWHNJEPSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50072569   

TargetMatrilysin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50072569((2R,3S)-2-Allyl-N*4*-((S)-1-benzyl-2-oxazol-2-yl-2...)
Affinity DataIC50:  4.20nMAssay Description:In vitro inhibitory activity against human recombinant matrix metalloproteinase 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50072569((2R,3S)-2-Allyl-N*4*-((S)-1-benzyl-2-oxazol-2-yl-2...)
Affinity DataIC50:  2.70nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase 1 isolated from the culture medium of human skin fibroblasts induced with PMAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50072569((2R,3S)-2-Allyl-N*4*-((S)-1-benzyl-2-oxazol-2-yl-2...)
Affinity DataIC50:  1.80nMAssay Description:In vitro inhibitory activity against human recombinant matrix metalloproteinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50072569((2R,3S)-2-Allyl-N*4*-((S)-1-benzyl-2-oxazol-2-yl-2...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50072569((2R,3S)-2-Allyl-N*4*-((S)-1-benzyl-2-oxazol-2-yl-2...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50072569((2R,3S)-2-Allyl-N*4*-((S)-1-benzyl-2-oxazol-2-yl-2...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50072569((2R,3S)-2-Allyl-N*4*-((S)-1-benzyl-2-oxazol-2-yl-2...)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50072569((2R,3S)-2-Allyl-N*4*-((S)-1-benzyl-2-oxazol-2-yl-2...)
Affinity DataIC50:  7.20nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase 2 isolated from human HT-1080 fibrosarcoma cells induced with TNFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed