BDBM50074159 (S)-4-[3-(2-{(S)-3-[((S)-1-Phenyl-ethylamino)-methyl]-pyrrolidin-1-yl}-ethyl)-1H-indol-5-ylmethyl]-oxazolidin-2-one::CHEMBL160070

SMILES C[C@H](NC[C@@H]1CCN(CCc2c[nH]c3ccc(C[C@H]4COC(=O)N4)cc23)C1)c1ccccc1

InChI Key InChIKey=IKUAJUBZHRXQPW-PTLVVNQVSA-N

Data  6 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50074159   

Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074159((S)-4-[3-(2-{(S)-3-[((S)-1-Phenyl-ethylamino)-meth...)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [3H]-5-HT binding from the cloned human 5-hydroxytryptamine 1D receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074159((S)-4-[3-(2-{(S)-3-[((S)-1-Phenyl-ethylamino)-meth...)
Affinity DataIC50:  49nMAssay Description:Displacement of [3H]-5-HT binding from the cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074159((S)-4-[3-(2-{(S)-3-[((S)-1-Phenyl-ethylamino)-meth...)
Affinity DataEC50:  0.5nMAssay Description:Stimulation of [35S]-GTP-gammaS, binding in CHO cells expressing the 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074159((S)-4-[3-(2-{(S)-3-[((S)-1-Phenyl-ethylamino)-meth...)
Affinity DataIC50:  50nMAssay Description:Affinity of compound towards 5-hydroxytryptamine 1B receptor was evaluated using radioligand binding techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074159((S)-4-[3-(2-{(S)-3-[((S)-1-Phenyl-ethylamino)-meth...)
Affinity DataIC50:  2.20E+3nMAssay Description:Affinity of compound towards human 5-hydroxytryptamine 2A receptor was evaluated using radioligand binding techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074159((S)-4-[3-(2-{(S)-3-[((S)-1-Phenyl-ethylamino)-meth...)
Affinity DataIC50:  0.300nMAssay Description:Affinity of compound towards 5-hydroxytryptamine 1D receptor was evaluated using radioligand binding techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074159((S)-4-[3-(2-{(S)-3-[((S)-1-Phenyl-ethylamino)-meth...)
Affinity DataIC50:  8.70nMAssay Description:Affinity of compound towards 5-hydroxytryptamine 1A receptor was evaluated using radioligand binding techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed