BDBM50075103 CHEBI:48202::Nanafrocin

SMILES C[C@@H]1O[C@@H](CC(O)=O)CC2=C1C(=O)c1c(O)cccc1C2=O

InChI Key InChIKey=ZCJHPTKRISJQTN-JGVFFNPUSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50075103   

TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50075103(CHEBI:48202 | Nanafrocin)
Affinity DataIC50:  500nMAssay Description:Inhibition of His6-tagged human recombinant DNMT3b expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-bio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50075103(CHEBI:48202 | Nanafrocin)
Affinity DataIC50:  730nMAssay Description:Inhibition of human recombinant DNMT3B expressed in baculovirus infected insect cells by DRONE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50075103(CHEBI:48202 | Nanafrocin)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human recombinant DNMT3B expressed in baculovirus infected insect cells using CpG site containing internally quenched hairpin oligonucl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50075103(CHEBI:48202 | Nanafrocin)
Affinity DataIC50:  500nMAssay Description:Inhibition of human DNMT3B using [3H]-SAMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed