BDBM50075318 2-(2-Chloro-4-methanesulfonyl-benzoyl)-3-hydroxy-cyclohex-2-enone::CHEMBL73467

SMILES CS(=O)(=O)c1ccc(C(=O)C2C(=O)CCCC2=O)c(Cl)c1

InChI Key InChIKey=PQTBTIFWAXVEPB-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50075318   

Target4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50075318(2-(2-Chloro-4-methanesulfonyl-benzoyl)-3-hydroxy-c...)
Affinity DataIC50:  50nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Arabidopsis thaliana)
Universit£

Curated by ChEMBL
LigandPNGBDBM50075318(2-(2-Chloro-4-methanesulfonyl-benzoyl)-3-hydroxy-c...)
Affinity DataIC50:  250nMAssay Description:Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli JM105 using 4-HPP as substrate preincubated for 15 mins followed by substrate a...More data for this Ligand-Target Pair
Target4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50075318(2-(2-Chloro-4-methanesulfonyl-benzoyl)-3-hydroxy-c...)
Affinity DataIC50:  45nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50075318(2-(2-Chloro-4-methanesulfonyl-benzoyl)-3-hydroxy-c...)
Affinity DataIC50:  45nMAssay Description:Inhibitory activity of the compound on pig liver 4-hydroxyphenylpyruvate dioxygenase (HPPD) was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed