BDBM50075651 1D-myo-inositol 1,3,4,5-tetrakis(dihydrogen phosphate)::1D-myo-inositol 1,3,4,5-tetrakisphosphate::CHEMBL23552

SMILES O[C@H]1[C@@H](OP(O)(O)=O)[C@H](O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H]1OP(O)(O)=O

InChI Key InChIKey=CIPFCGZLFXVXBG-CNWJWELYSA-N

Data  3 IC50  1 Kd

PDB links: 28 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50075651   

TargetInositol 1,4,5-trisphosphate receptor type 3(Homo sapiens (Human))
Bergische UniversitäT Wuppertal

Curated by ChEMBL
LigandPNGBDBM50075651(1D-myo-inositol 1,3,4,5-tetrakis(dihydrogen phosph...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of Ins(1,3,4,5)P4-PtdIns(3,4,5)P3-specific receptor from Pig cerebellum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
University Of East Anglia

Curated by ChEMBL
LigandPNGBDBM50075651(1D-myo-inositol 1,3,4,5-tetrakis(dihydrogen phosph...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of 2-FAM-InsP5 binding to human SHIP2 catalytic domain (419 to 832 residues) assessed as change in polarization by fluorescence polarizati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInositol-trisphosphate 3-kinase A(Rattus norvegicus)
Pohang University Of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50075651(1D-myo-inositol 1,3,4,5-tetrakis(dihydrogen phosph...)
Affinity DataIC50:  2.78E+4nMAssay Description:Binding affinity of the compound against recombinant plasmid rat brain IP3K by overexpressing in E. coliMore data for this Ligand-Target Pair
TargetCytohesin-3(Rattus norvegicus)
Kumamoto Health Science University

Curated by ChEMBL
LigandPNGBDBM50075651(1D-myo-inositol 1,3,4,5-tetrakis(dihydrogen phosph...)
Affinity DataKd:  100nMAssay Description:Binding affinity to recombinant rat brain Grp1 PH domain (amino acids 1 to 120) after 10 mins by pull-down assayMore data for this Ligand-Target Pair