BDBM50076938 2-[1,11-dihydroxy-5,7-dioxo-12-(3,4,5-trihydroxy-6-hydroxymethyltetrahydro-2H-2-pyranyl)-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-6-ylamino]ethyl cyanide::CHEMBL283766

SMILES OCC1OC(C(O)C(O)C1O)n1c2c(O)cccc2c2c3C(=O)N(NCCC#N)C(=O)c3c3c4cccc(O)c4[nH]c3c12

InChI Key InChIKey=HZRSZAGJTWDOMR-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50076938   

TargetProtein kinase C alpha type(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50076938(2-[1,11-dihydroxy-5,7-dioxo-12-(3,4,5-trihydroxy-6...)
Affinity DataIC50: >2.00E+5nMAssay Description:In vitro activity evaluated against protein kinase C (using histone II-As as a substrate)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50076938(2-[1,11-dihydroxy-5,7-dioxo-12-(3,4,5-trihydroxy-6...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro activity against topoisomerase-2 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50076938(2-[1,11-dihydroxy-5,7-dioxo-12-(3,4,5-trihydroxy-6...)
Affinity DataEC50:  70nMAssay Description:In vitro activity against topoisomerase-I mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50076938(2-[1,11-dihydroxy-5,7-dioxo-12-(3,4,5-trihydroxy-6...)
Affinity DataIC50: >2.00E+5nMAssay Description:In vitro activity against Epidermal growth factor receptor (using poly(Glu4Tyr1) as a substrate)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed