BDBM50079716 (5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hexaenoic acid (2,6-diisopropyl-phenyl)-amide::CHEMBL304267

SMILES C\C=C\C\C=C\C\C=C\C\C=C\C\C=C\C\C=C\CCCC(=O)Nc1c(cccc1C(C)C)C(C)C

InChI Key InChIKey=PURDMSRYPDDRFJ-BUHCESQUSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50079716   

TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Azwell

Curated by ChEMBL
LigandPNGBDBM50079716((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...)
Affinity DataIC50:  228nMAssay Description:Compound was tested for inhibitory activity against ACAT from Caco-2 microsome in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Azwell

Curated by ChEMBL
LigandPNGBDBM50079716((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...)
Affinity DataIC50:  36nMAssay Description:Compound was tested for inhibitory activity against ACAT from rabbit liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Azwell

Curated by ChEMBL
LigandPNGBDBM50079716((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...)
Affinity DataIC50:  36nMAssay Description:Compound was tested for inhibitory activity against ACAT from canine adrenal glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Azwell

Curated by ChEMBL
LigandPNGBDBM50079716((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...)
Affinity DataIC50:  7.24E+3nMAssay Description:Compound was tested for inhibitory activity against ACAT from U937 microsome in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Azwell

Curated by ChEMBL
LigandPNGBDBM50079716((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...)
Affinity DataIC50:  56nMAssay Description:Compound was tested for inhibitory activity against ACAT from canine intestineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Azwell

Curated by ChEMBL
LigandPNGBDBM50079716((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...)
Affinity DataIC50:  35nMAssay Description:Compound was tested for inhibitory activity against ACAT from canine liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Azwell

Curated by ChEMBL
LigandPNGBDBM50079716((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...)
Affinity DataIC50:  45nMAssay Description:Compound was tested for inhibitory activity against ACAT from rabbit intestineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Azwell

Curated by ChEMBL
LigandPNGBDBM50079716((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...)
Affinity DataIC50:  3.57E+3nMAssay Description:Compound was tested for inhibitory activity against ACAT from canine liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Azwell

Curated by ChEMBL
LigandPNGBDBM50079716((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...)
Affinity DataIC50:  43nMAssay Description:Compound was tested for inhibitory activity against ACAT from rabbit liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed