BDBM50079855 (R)-2-[2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-d]furan-11-yl)-phenoxy]-3-phenyl-propionic acid::CHEMBL324232

SMILES OC(=O)[C@@H](Cc1ccccc1)Oc1c(Br)cc(cc1Br)-c1c2c3ccccc3oc2c(Br)c2ccccc12

InChI Key InChIKey=WWEKHDAAECLWTK-RUZDIDTESA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50079855   

TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079855((R)-2-[2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-...)
Affinity DataIC50:  500nMAssay Description:The compound was tested in vitro for the inhibitory activity against Protein-tyrosine phosphatase beta (SH-PTP1) (human PTPases.)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079855((R)-2-[2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-...)
Affinity DataIC50:  80nMAssay Description:The compound was tested in vitro for the inhibitory activity against hPTP1B (human PTPases.)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 12(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079855((R)-2-[2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-...)
Affinity DataIC50:  2.20E+3nMAssay Description:The compound was tested in vitro for the inhibitory activity against Protein tyrosine phosphatase PEST (SH-PTP1) (human PTPases.)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079855((R)-2-[2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-...)
Affinity DataIC50:  9.00E+3nMAssay Description:The compound was tested in vitro for the inhibitory activity against Protein-tyrosine phosphatase 1C (SH-PTP1) (human PTPases.)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079855((R)-2-[2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-...)
Affinity DataIC50:  870nMAssay Description:Inhibition of GST-tagged recombinant human PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079855((R)-2-[2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-...)
Affinity DataIC50:  1.30E+4nMAssay Description:The compound was tested in vitro for the inhibitory activity against Protein-tyrosine phosphatase 1 alpha (LRP) (human PTPases.)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079855((R)-2-[2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-...)
Affinity DataIC50:  83nMAssay Description:The compound was tested in vitro for the inhibitory activity against Protein-tyrosine phosphatase 1B (human PTPases.)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079855((R)-2-[2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-...)
Affinity DataIC50:  6.30E+3nMAssay Description:The compound was tested in vitro for the inhibitory activity against CD45 antigen (human PTPases.)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079855((R)-2-[2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-...)
Affinity DataIC50:  1.10E+4nMAssay Description:The compound was tested in vitro for the inhibitory activity against Dual specificity protein phosphatase 3 (SH-PTP1) (human PTPases.)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079855((R)-2-[2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-...)
Affinity DataIC50:  420nMAssay Description:The compound was tested in vitro for the inhibitory activity against LAR (human Protein-tyrosine phosphatase F)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed