BDBM50082220 (2R,3S)-N*1*-((S)-1-Carbamoyl-2-phenyl-ethyl)-2-(6-fluoro-naphthalen-2-ylmethyl)-3,N*4*-dihydroxy-succinamide::CHEMBL108412

SMILES NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc2cc(F)ccc2c1)[C@H](O)C(=O)NO

InChI Key InChIKey=OYZQESBTDIZNIE-HKBOAZHASA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50082220   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082220((2R,3S)-N*1*-((S)-1-Carbamoyl-2-phenyl-ethyl)-2-(6...)
Affinity DataIC50:  850nMAssay Description:Inhibitory activity against matrix metalloproteinase(MMP-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082220((2R,3S)-N*1*-((S)-1-Carbamoyl-2-phenyl-ethyl)-2-(6...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against matrix metalloproteinase(MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082220((2R,3S)-N*1*-((S)-1-Carbamoyl-2-phenyl-ethyl)-2-(6...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of matrix metalloproteinase(MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082220((2R,3S)-N*1*-((S)-1-Carbamoyl-2-phenyl-ethyl)-2-(6...)
Affinity DataIC50:  220nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed