BDBM50082225 (2R,3S)-N*4*-((S)-1-Carbamoyl-2,2-dimethyl-propyl)-2,N*1*-dihydroxy-3-quinolin-3-ylmethyl-succinamide::CHEMBL323228

SMILES CC(C)(C)[C@H](NC(=O)[C@H](Cc1cnc2ccccc2c1)[C@H](O)C(=O)NO)C(N)=O

InChI Key InChIKey=IJCQDLHWIZVIEL-VNQPRFMTSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50082225   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082225((2R,3S)-N*4*-((S)-1-Carbamoyl-2,2-dimethyl-propyl)...)
Affinity DataIC50:  190nMAssay Description:Inhibitory activity against matrix metalloproteinase(MMP-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082225((2R,3S)-N*4*-((S)-1-Carbamoyl-2,2-dimethyl-propyl)...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibitory activity against matrix metalloproteinase(MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082225((2R,3S)-N*4*-((S)-1-Carbamoyl-2,2-dimethyl-propyl)...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of matrix metalloproteinase(MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082225((2R,3S)-N*4*-((S)-1-Carbamoyl-2,2-dimethyl-propyl)...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed