BDBM50087690 8-Bicyclohexyl-4-yl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL354065

SMILES O=C1NCN(c2ccccc2)C11CCN(CC1)[C@@H]1CC[C@@H](CC1)C1CCCCC1

InChI Key InChIKey=PKXNDSOXWCRAIK-SZPZYZBQSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50087690   

TargetNociceptin receptor(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087690(8-Bicyclohexyl-4-yl-1-phenyl-1,3,8-triaza-spiro[4....)
Affinity DataKi:  1.5nMAssay Description:Inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat Opioid receptor like 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087690(8-Bicyclohexyl-4-yl-1-phenyl-1,3,8-triaza-spiro[4....)
Affinity DataKi:  1.5nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087690(8-Bicyclohexyl-4-yl-1-phenyl-1,3,8-triaza-spiro[4....)
Affinity DataKi:  29nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087690(8-Bicyclohexyl-4-yl-1-phenyl-1,3,8-triaza-spiro[4....)
Affinity DataKi:  330nMAssay Description:Inhibition against binding of radioligand [Ile5,6-3H]-deltorphin to membrane from baby hamster kidney cells infected with forest virus encoding the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed