BDBM50089221 CHEMBL3577854

SMILES CCNC(=O)NCCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12

InChI Key InChIKey=CACMCLIHCDTJHL-IDTAVKCVSA-N

Data  5 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50089221   

TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50089221(CHEMBL3577854)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human full length PRMT5 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 7(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50089221(CHEMBL3577854)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human full length PRMT7 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50089221(CHEMBL3577854)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human full length DNMT3A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 7(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50089221(CHEMBL3577854)
Affinity DataKd:  3.70E+4nMAssay Description:Binding affinity to human full length PRMT7 by Surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 7(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50089221(CHEMBL3577854)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human full length PRMT7 expressed in Sf9 cells assessed as inhibition of H2B[23-37] methylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50089221(CHEMBL3577854)
Affinity DataKd:  2.50E+4nMAssay Description:Binding affinity to human full length PRMT5-MEP50 complex by Surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50089221(CHEMBL3577854)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human full length DNMT3B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed