BDBM50089221 CHEMBL3577854
SMILES CCNC(=O)NCCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
InChI Key InChIKey=CACMCLIHCDTJHL-IDTAVKCVSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50089221
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human full length PRMT5 expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 7(Homo sapiens (Human))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human full length PRMT7 expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetDNA (cytosine-5)-methyltransferase 3A(Homo sapiens (Human))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human full length DNMT3A expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 7(Homo sapiens (Human))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKd: 3.70E+4nMAssay Description:Binding affinity to human full length PRMT7 by Surface plasmon resonance methodMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 7(Homo sapiens (Human))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human full length PRMT7 expressed in Sf9 cells assessed as inhibition of H2B[23-37] methylationMore data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKd: 2.50E+4nMAssay Description:Binding affinity to human full length PRMT5-MEP50 complex by Surface plasmon resonance methodMore data for this Ligand-Target Pair
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human full length DNMT3B expressed in Sf9 cellsMore data for this Ligand-Target Pair