BDBM50090510 CHEMBL3581716

SMILES CC(=O)Nc1cc(cc2CCN(CCc3ccccc3)c12)S(=O)(=O)Nc1ccc(F)cc1F

InChI Key InChIKey=XVSKYVJHKGLQMZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50090510   

TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50090510(CHEMBL3581716)
Affinity DataIC50:  3.50E+4nMAssay Description:In vitro inhibition of full length human ACAT1 transfected in Sf-21 cells using [1-14C]oleoyl-CoA assessed as incorporation of radioactivity into lip...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50090510(CHEMBL3581716)
Affinity DataIC50: >3.00E+4nMAssay Description:In vitro inhibition of full length human DGAT2 transfected in Sf-21 cells using [1-14C]oleoyl-CoA assessed as incorporation of radioactivity into lip...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50090510(CHEMBL3581716)
Affinity DataIC50:  1nMAssay Description:In vitro inhibition of full length human MGAT2 transfected in FreeStyle293 cells assessed as dioleoylglycerol by RapidFire/MS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50090510(CHEMBL3581716)
Affinity DataIC50: >3.00E+4nMAssay Description:In vitro inhibition of full length human MGAT3 transfected in Sf-21 cells using [1-14C]oleoyl-CoA assessed as incorporation of radioactivity into lip...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50090510(CHEMBL3581716)
Affinity DataIC50: >3.00E+4nMAssay Description:In vitro inhibition of full length human DGAT1 transfected in Sf-21 cells using [1-14C]oleoyl-CoA assessed as incorporation of radioactivity into lip...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed