BDBM50092470 CHEMBL3586131

SMILES Cl.[H][C@@]12COC[C@]3(CC[C@@H](C[C@]13[H])NC(=O)c1cccc(Cl)c1)N=C(N)S2

InChI Key InChIKey=SLYXQQNGVHPIRQ-CFAJVAMVSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50092470   

TargetCathepsin D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50092470(CHEMBL3586131)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50092470(CHEMBL3586131)
Affinity DataIC50:  2.25E+3nMAssay Description:Inhibition of human BACE1 by mcaFRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50092470(CHEMBL3586131)
Affinity DataIC50:  1.34E+3nMAssay Description:Inhibition of human BACE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed