BDBM50092632 8-(3-Nitro-phenyl)-6-pyridin-4-ylmethyl-quinoline::8-(3-nitrophenyl)-6-(pyridin-4-ylmethyl)quinoline::CHEMBL127944

SMILES [O-][N+](=O)c1cccc(c1)-c1cc(Cc2ccncc2)cc2cccnc12

InChI Key InChIKey=XRSKAWJXBDACRF-UHFFFAOYSA-N

Data  3 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50092632   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50092632(8-(3-Nitro-phenyl)-6-pyridin-4-ylmethyl-quinoline ...)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of recombinant human PDE4A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50092632(8-(3-Nitro-phenyl)-6-pyridin-4-ylmethyl-quinoline ...)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of recombinant human PDE4B catalytic domain expressed in baculovirus infected sf9 cells using cAMP as substrateMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50092632(8-(3-Nitro-phenyl)-6-pyridin-4-ylmethyl-quinoline ...)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of recombinant human PDE4B catalytic domain expressed in baculovirus infected sf9 cells using cAMP as substrateMore data for this Ligand-Target Pair