BDBM50094602 CHEMBL3589010::US9284299, iCRT14::US9738628, Compound iCRT14

SMILES Cc1cc(\C=C2/SC(=O)N(C2=O)c2ccccc2)c(C)n1-c1cccnc1

InChI Key InChIKey=SIWILKNHDXXHHI-FQEVSTJZSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50094602   

TargetCatenin beta-1 [138-686](Homo sapiens (Human))
University Of Utah Research Foundation

US Patent
LigandPNGBDBM50094602(CHEMBL3589010 | US9284299, iCRT14 | US9738628, Com...)
Affinity DataKi:  4.07E+4nM ΔG°:  -5.99kcal/molepH: 7.4 T: 2°CAssay Description:Experiments were performed in white opaque 384-well plates from PerkinElmer (Waltham, Mass.), and the samples were read on a Synergy 2 plate reader (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCatenin beta-1 [138-686](Homo sapiens (Human))
University Of Utah Research Foundation

US Patent
LigandPNGBDBM50094602(CHEMBL3589010 | US9284299, iCRT14 | US9738628, Com...)
Affinity DataKi:  4.07E+4nMAssay Description:Experiments were performed in 96-well Microfluor 2 black plates (Waltham, Mass.), and the samples were read by a Synergy 2 plate reader (Biotek, Wino...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCatenin beta-1 [138-686](Homo sapiens (Human))
University Of Utah Research Foundation

US Patent
LigandPNGBDBM50094602(CHEMBL3589010 | US9284299, iCRT14 | US9738628, Com...)
Affinity DataKi:  5.35E+4nM ΔG°:  -5.82kcal/moleT: 2°CAssay Description:Experiments were performed in 96-well Microfluor 2 black plates (Waltham, Mass.), and the samples were read by a Synergy 2 plate reader (Biotek, Wino...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCatenin beta-1 [138-686](Homo sapiens (Human))
University Of Utah Research Foundation

US Patent
LigandPNGBDBM50094602(CHEMBL3589010 | US9284299, iCRT14 | US9738628, Com...)
Affinity DataKi:  5.35E+4nMAssay Description:Experiments were performed in white opaque 384-well plates from PerkinElmer (Waltham, Mass.), and the samples were read on a Synergy 2 plate reader (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCatenin beta-1(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50094602(CHEMBL3589010 | US9284299, iCRT14 | US9738628, Com...)
Affinity DataKi:  5.40E+4nMAssay Description:Inhibition of human wild-type beta-catenin (residues 138-686)/C-terminally fluorescein labeled human wild-type Tcf4 (residues 7-51) interaction after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed