BDBM50095293 CHEMBL3589085::US9278953, 13

SMILES CCn1ncc2c(C)cc(cc12)-c1ccc(c(=O)[nH]1)[C@@]1(C)CCNC1=O

InChI Key InChIKey=JHDASKCSVXZNSZ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50095293   

TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50095293(CHEMBL3589085 | US9278953, 13)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor expressed in CHO cells by radioligand competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50095293(CHEMBL3589085 | US9278953, 13)
Affinity DataKi:  31.6nM ΔG°:  -10.2kcal/molepH: 7.4 T: 2°CAssay Description:Test compounds were half log serially diluted in 100% DMSO (J. T. Baker #922401). 1 uL of each compound was added to appropriate wells of a 384-well ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50095293(CHEMBL3589085 | US9278953, 13)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor by MicroBeta plate-based scintillation counting/SPA binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed