BDBM50095293 CHEMBL3589085::US9278953, 13
SMILES CCn1ncc2c(C)cc(cc12)-c1ccc(c(=O)[nH]1)[C@@]1(C)CCNC1=O
InChI Key InChIKey=JHDASKCSVXZNSZ-UHFFFAOYSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50095293
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor expressed in CHO cells by radioligand competition binding assayMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataKi: 31.6nM ΔG°: -10.2kcal/molepH: 7.4 T: 2°CAssay Description:Test compounds were half log serially diluted in 100% DMSO (J. T. Baker #922401). 1 uL of each compound was added to appropriate wells of a 384-well ...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataKi: 32nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor by MicroBeta plate-based scintillation counting/SPA binding assayMore data for this Ligand-Target Pair