BDBM50095435 CHEMBL3590417

SMILES CNCCN(C)Cc1n[nH]cc1-c1ccc(Oc2ccccc2C(=O)NC)cc1

InChI Key InChIKey=LIVCXRSDQOQURR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50095435   

TargetProtein arginine N-methyltransferase 8(Homo sapiens (Human))
Epizyme

Curated by ChEMBL
LigandPNGBDBM50095435(CHEMBL3590417)
Affinity DataIC50:  65nMAssay Description:Inhibition of N-terminal GST tagged full-length human PRMT8 expressed in Escherichia coli (BL21(DE3) pre-incubated for 30 mins before addition of a [...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
Epizyme

Curated by ChEMBL
LigandPNGBDBM50095435(CHEMBL3590417)
Affinity DataIC50:  50nMAssay Description:Inhibition of N-terminal GST tagged full-length human PRMT1 expressed in high five insect cells pre-incubated for 30 mins before addition of a [3H]SA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
Epizyme

Curated by ChEMBL
LigandPNGBDBM50095435(CHEMBL3590417)
Affinity DataIC50:  5nMAssay Description:Inhibition of FLAG and hexa-histidine tagged full-length human PRMT6 expressed in HEK293F cells pre-incubated for 30 mins before addition of a [3H]SA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed