BDBM50096463 CHEMBL70176::N-Hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3-methyl-benzamide::N-hydroxy-2-(4-methoxy-N-(pyridin-3-ylmethyl)phenylsulfonamido)-3-methylbenzamide

SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cccc1C(=O)NO

InChI Key InChIKey=AINJYWXKBKRQSX-UHFFFAOYSA-N

Data  24 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50096463   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(CHEMBL70176 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)
Affinity DataIC50:  356nMAssay Description:In vitro inhibition of TNF-alpha converting enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50096463(CHEMBL70176 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(CHEMBL70176 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)
Affinity DataIC50:  231nMAssay Description:In vitro inhibition of TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(CHEMBL70176 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)
Affinity DataIC50:  5nMAssay Description:In vitro ability to inhibit matrix metalloprotease-9.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50096463(CHEMBL70176 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)
Affinity DataIC50:  8nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50096463(CHEMBL70176 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)
Affinity DataIC50:  8nMAssay Description:Inhibitory activity against Matrix metalloprotease-13More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(CHEMBL70176 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)
Affinity DataIC50:  143nMAssay Description:Inhibitory activity against Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(CHEMBL70176 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity against Matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50096463(CHEMBL70176 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)
Affinity DataIC50:  8nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(CHEMBL70176 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)
Affinity DataIC50:  143nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(CHEMBL70176 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)
Affinity DataIC50:  5nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(CHEMBL70176 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)
Affinity DataIC50:  7nMAssay Description:In vitro inhibition of Matrix metalloprotease-9.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50096463(CHEMBL70176 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)
Affinity DataIC50:  18nMAssay Description:In vitro inhibition of Matrix metalloprotease-13.More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(CHEMBL70176 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)
Affinity DataIC50:  329nMAssay Description:In vitro inhibition of Matrix metalloprotease-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(CHEMBL70176 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)
Affinity DataIC50:  8nMAssay Description:In vitro inhibition of Matrix metalloprotease-13.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(CHEMBL70176 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)
Affinity DataIC50:  7nMAssay Description:In vitro inhibition of Matrix metalloprotease-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(CHEMBL70176 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)
Affinity DataIC50:  356nMAssay Description:In vitro inhibition of Matrix metalloprotease-9.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(CHEMBL70176 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)
Affinity DataIC50:  645nMAssay Description:In vitro inhibition of TNF-alpha converting enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(CHEMBL70176 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)
Affinity DataIC50:  391nMAssay Description:In vitro inhibition of Matrix metalloprotease-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(CHEMBL70176 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)
Affinity DataIC50:  329nMAssay Description:In vitro inhibition of Matrix metalloprotease-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50096463(CHEMBL70176 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)
Affinity DataIC50:  18nMAssay Description:In vitro inhibition of Matrix metalloprotease-13.More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50096463(CHEMBL70176 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)
Affinity DataIC50:  18nMAssay Description:In vitro inhibition of Matrix metalloprotease-13.More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(CHEMBL70176 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)
Affinity DataIC50:  5nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(CHEMBL70176 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)
Affinity DataIC50:  143nMAssay Description:In vitro inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed