BDBM50099697 7-(9,10-Dioxo-9,10-dihydro-phenanthren-2-ylcarbamoyl)-heptanoic acid methyl ester::CHEMBL50347

SMILES COC(=O)CCCCCCC(=O)Nc1ccc2-c3ccccc3C(=O)C(=O)c2c1

InChI Key InChIKey=AVAFSDMMBPCFKE-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50099697   

TargetTyrosine-protein phosphatase non-receptor type 13(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099697(7-(9,10-Dioxo-9,10-dihydro-phenanthren-2-ylcarbamo...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration against FAP-1 using lck-10 mer as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099697(7-(9,10-Dioxo-9,10-dihydro-phenanthren-2-ylcarbamo...)
Affinity DataIC50:  500nMAssay Description:In vitro inhibitory activity against the cytosolic portion of CD45 protein-tyrosine phosphatase using pNPP as the substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099697(7-(9,10-Dioxo-9,10-dihydro-phenanthren-2-ylcarbamo...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibitory concentration against CD45 protein-tyrosine phosphatase using lck-10mer as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 13(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099697(7-(9,10-Dioxo-9,10-dihydro-phenanthren-2-ylcarbamo...)
Affinity DataIC50:  9.90E+3nMAssay Description:Inhibitory concentration against FAP-1 pNPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099697(7-(9,10-Dioxo-9,10-dihydro-phenanthren-2-ylcarbamo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against Cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099697(7-(9,10-Dioxo-9,10-dihydro-phenanthren-2-ylcarbamo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099697(7-(9,10-Dioxo-9,10-dihydro-phenanthren-2-ylcarbamo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed