BDBM50099736 4-Ethoxy-[1,2]naphthoquinone::4-ethoxynaphthalene-1,2-dione::CHEMBL50620

SMILES CCOC1=CC(=O)C(=O)c2ccccc12

InChI Key InChIKey=XPXODXIULRDWNT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50099736   

TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099736(4-Ethoxy-[1,2]naphthoquinone | 4-ethoxynaphthalene...)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro inhibitory activity against the cytosolic portion of CD45 protein-tyrosine phosphatase using pNPP as the substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 6(Rattus norvegicus)
Virginia Polytechnic Institute And State University

Curated by ChEMBL
LigandPNGBDBM50099736(4-Ethoxy-[1,2]naphthoquinone | 4-ethoxynaphthalene...)
Affinity DataIC50:  1.35E+3nMAssay Description:Inhibition of histidine-tagged rat recombinant MKP3 catalytic domain expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 1(Mus musculus)
Virginia Polytechnic Institute And State University

Curated by ChEMBL
LigandPNGBDBM50099736(4-Ethoxy-[1,2]naphthoquinone | 4-ethoxynaphthalene...)
Affinity DataIC50:  820nMAssay Description:Inhibition of histidine-tagged mouse MKP1 catalytic domain expressed in human Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Virginia Polytechnic Institute And State University

Curated by ChEMBL
LigandPNGBDBM50099736(4-Ethoxy-[1,2]naphthoquinone | 4-ethoxynaphthalene...)
Affinity DataIC50:  270nMAssay Description:Inhibition of histidine-tagged human recombinant Cdc25B catalytic domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed