BDBM50100479 CHEMBL303751::N-(4-Hydroxy-5-hydroxymethyl-2-{6-[(3-hydroxy-naphthalen-1-ylmethyl)-amino]-9H-purin-3-ylmethyl}-tetrahydro-furan-3-yl)-3,5-dimethoxy-benzamide

SMILES COc1cc(OC)cc(c1)C(=O)N[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(NCc3cc(O)cc4ccccc34)ncnc12

InChI Key InChIKey=MCYLUJCIHWOOIO-JVUUKAHWSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50100479   

TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50100479(CHEMBL303751 | N-(4-Hydroxy-5-hydroxymethyl-2-{6-[...)
Affinity DataIC50:  8.00E+3nMAssay Description:In vitro inhibition of Trypanosoma brucei GAPDH.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50100479(CHEMBL303751 | N-(4-Hydroxy-5-hydroxymethyl-2-{6-[...)
Affinity DataIC50:  1.00E+4nMAssay Description:In vitro inhibition of Trypanosoma cruzi GAPDH.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase, cytosolic(Leishmania mexicana)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50100479(CHEMBL303751 | N-(4-Hydroxy-5-hydroxymethyl-2-{6-[...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against Leishmania mexicana GAPDHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50100479(CHEMBL303751 | N-(4-Hydroxy-5-hydroxymethyl-2-{6-[...)
Affinity DataIC50: >5.00E+4nMAssay Description:In vitro inhibition of rabbit muscle GAPDH.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed