BDBM50102594 7-Isobutyl-8-oxo-2-oxa-9-aza-bicyclo[10.2.2]hexadeca-1(15),12(16),13-triene-6,10-dicarboxylic acid 6-hydroxyamide 10-methylcarbamoylmethyl-amide(SL422)::CHEMBL88520
SMILES CNC(=O)CNC(=O)[C@@H]1Cc2ccc(OCCC[C@@H]([C@@H](CC(C)C)C(=O)N1)C(=O)NO)cc2
InChI Key InChIKey=HFAGTNGCAZYYLZ-OTWHNJEPSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50102594
Affinity DataKi: 0.450nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of matrix metalloprotease-7More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:In vitro inhibition of human MMP-9.More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:In vitro inhibition of human MMP-1.More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Inhibition of porcine TNF-alpha converting enzyme (pTACE).More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition of human MMP-3.More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of matrix metalloprotease-15More data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Inhibition of matrix metalloprotease-16More data for this Ligand-Target Pair
Affinity DataKi: 94nMAssay Description:Inhibition of matrix metalloprotease-14More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of LPS-stimulated TNF-alpha release in human whole bloodMore data for this Ligand-Target Pair