BDBM50103988 4-Benzylsulfanyl-2-[{[(di-pyridin-2-yl-methyl)-carbamoyl]-methyl}-(4-methoxy-benzenesulfonyl)-amino]-N-hydroxy-butyramide::CHEMBL105311

SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NC(c1ccccn1)c1ccccn1)C(CCSCc1ccccc1)C(=O)NO

InChI Key InChIKey=SWRNCXLTVBBIMK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50103988   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50103988(4-Benzylsulfanyl-2-[{[(di-pyridin-2-yl-methyl)-car...)
Affinity DataIC50:  0.200nMAssay Description:In vitro inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50103988(4-Benzylsulfanyl-2-[{[(di-pyridin-2-yl-methyl)-car...)
Affinity DataIC50:  39nMAssay Description:In vitro inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50103988(4-Benzylsulfanyl-2-[{[(di-pyridin-2-yl-methyl)-car...)
Affinity DataIC50:  0.400nMAssay Description:In vitro inhibition of human matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50103988(4-Benzylsulfanyl-2-[{[(di-pyridin-2-yl-methyl)-car...)
Affinity DataIC50:  1.10nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50103988(4-Benzylsulfanyl-2-[{[(di-pyridin-2-yl-methyl)-car...)
Affinity DataIC50:  0.400nMAssay Description:In vitro inhibition of human matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed