BDBM50104006 4-Benzylsulfanyl-N-hydroxy-2-[isobutyl-(4-methoxy-benzenesulfonyl)-amino]-butyramide::CHEMBL320402

SMILES COc1ccc(cc1)S(=O)(=O)N(CC(C)C)[C@H](CCSCc1ccccc1)C(=O)NO

InChI Key InChIKey=TWQZYQBXMVVVCY-OAQYLSRUSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50104006   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50104006(4-Benzylsulfanyl-N-hydroxy-2-[isobutyl-(4-methoxy-...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50104006(4-Benzylsulfanyl-N-hydroxy-2-[isobutyl-(4-methoxy-...)
Affinity DataIC50:  104nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50104006(4-Benzylsulfanyl-N-hydroxy-2-[isobutyl-(4-methoxy-...)
Affinity DataIC50:  12nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50104006(4-Benzylsulfanyl-N-hydroxy-2-[isobutyl-(4-methoxy-...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50104006(4-Benzylsulfanyl-N-hydroxy-2-[isobutyl-(4-methoxy-...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed