BDBM50106086 (S)-3-(3,4-Dimethoxy-phenyl)-3-[2-((3-methoxy-propyl)-{2-[4-(3-o-tolyl-ureido)-phenyl]-acetyl}-amino)-acetylamino]-propionic acid::CHEMBL316723

SMILES COCCCN(CC(=O)N[C@@H](CC(O)=O)c1ccc(OC)c(OC)c1)C(=O)Cc1ccc(NC(=O)Nc2ccccc2C)cc1

InChI Key InChIKey=GBTYEOLOCAQPPZ-MHZLTWQESA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50106086   

TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50106086((S)-3-(3,4-Dimethoxy-phenyl)-3-[2-((3-methoxy-prop...)
Affinity DataIC50:  27nMAssay Description:Inhibition of fluorescent Ramos cell adhesion to VCAM-1 by mouse Very late antigen 4 (VLA-4) integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50106086((S)-3-(3,4-Dimethoxy-phenyl)-3-[2-((3-methoxy-prop...)
Affinity DataIC50:  22nMAssay Description:Inhibition of fluorescent Ramos cell adhesion to VCAM-1 by rat Very late antigen 4 (VLA-4) integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50106086((S)-3-(3,4-Dimethoxy-phenyl)-3-[2-((3-methoxy-prop...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of fluorescent Ramos cell adhesion to VCAM-1 by alpha4-beta7 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50106086((S)-3-(3,4-Dimethoxy-phenyl)-3-[2-((3-methoxy-prop...)
Affinity DataIC50:  7.10nMAssay Description:In vitro Very late antigen 4 cell adhesion inhibitory activity measured by binding of fluorescently labeled Ramos cells to immobilized VCAM-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50106086((S)-3-(3,4-Dimethoxy-phenyl)-3-[2-((3-methoxy-prop...)
Affinity DataIC50:  13nMAssay Description:Inhibition of fluorescent Ramos cell adhesion to fibronectin by Very late antigen 5 (VLA-5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50106086((S)-3-(3,4-Dimethoxy-phenyl)-3-[2-((3-methoxy-prop...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of fluorescent Ramos cell adhesion to fibronectin by Very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed