BDBM50106305 2-Phenyl-3H-quinazolin-4-one::2-phenyl-3,4-dihydroquinazolin-4-one (29)::CHEMBL127066

SMILES O=c1[nH]c(nc2ccccc12)-c1ccccc1

InChI Key InChIKey=VDULOAUXSMYUMG-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50106305   

TargetChymotrypsinogen A(Bos taurus (bovine))
University Of Karachi

LigandPNGBDBM50106305(2-Phenyl-3H-quinazolin-4-one | 2-phenyl-3,4-dihydr...)
Affinity DataIC50: >5.00E+5nMpH: 7.6Assay Description:The α-chymotrypsin inhibition activity was evaluated in 50 mM Tris-HCl buffer pH 7.6 with 10 mM CaCl2. α-Chymotrypsin (bovine pancreas) at ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50106305(2-Phenyl-3H-quinazolin-4-one | 2-phenyl-3,4-dihydr...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of tubulin polymerization.(ITP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50106305(2-Phenyl-3H-quinazolin-4-one | 2-phenyl-3,4-dihydr...)
Affinity DataIC50:  1.77E+5nMAssay Description:Inhibition of beta-glucuronidase activity (unknown origin) assessed as p-nitrophenol formation after 30 mins using p-nitrophenyl-beta-D-glucuronide a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed