BDBM50107169 1-{3-[4-(1-Methyl-1H-indol-5-ylsulfanyl)-2,3-bis-trifluoromethyl-phenyl]-acryloyl}-piperidine-4-carboxylic acid::CHEMBL343390

SMILES Cn1ccc2cc(Sc3ccc(\C=C\C(=O)N4CCC(CC4)C(O)=O)c(c3C(F)(F)F)C(F)(F)F)ccc12

InChI Key InChIKey=QCABIGRYALYSAQ-XVNBXDOJSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107169   

TargetIntegrin alpha-L(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107169(1-{3-[4-(1-Methyl-1H-indol-5-ylsulfanyl)-2,3-bis-t...)
Affinity DataIC50:  5nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(5-5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107169(1-{3-[4-(1-Methyl-1H-indol-5-ylsulfanyl)-2,3-bis-t...)
Affinity DataIC50:  5nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range(3-10)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed