BDBM50107171 1-{3-[2,3-Dichloro-4-(2-methoxy-phenylsulfanyl)-phenyl]-acryloyl}-piperidine-4-carboxylic acid::CHEMBL140085

SMILES COc1ccccc1Sc1ccc(\C=C\C(=O)N2CCC(CC2)C(O)=O)c(Cl)c1Cl

InChI Key InChIKey=QPWDZBBZIVDASP-VQHVLOKHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107171   

TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107171(1-{3-[2,3-Dichloro-4-(2-methoxy-phenylsulfanyl)-ph...)
Affinity DataIC50:  8nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range (2-30)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107171(1-{3-[2,3-Dichloro-4-(2-methoxy-phenylsulfanyl)-ph...)
Affinity DataIC50:  8nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range (6-12)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed