BDBM50109750 2-Dibutylamino-1-{2,7-dichloro-9-[1-(4-chloro-phenyl)-meth-(E)-ylidene]-9H-fluoren-4-yl}-ethanol::CHEMBL422330::LUMEFANTRINE

SMILES CCCCN(CCCC)CC(O)c1cc(Cl)cc2\C(=C\c3ccc(Cl)cc3)c3cc(Cl)ccc3-c12

InChI Key InChIKey=DYLGFOYVTXJFJP-MFKUBSTISA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50109750   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM50109750(2-Dibutylamino-1-{2,7-dichloro-9-[1-(4-chloro-phen...)
Affinity DataIC50:  8.13E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM50109750(2-Dibutylamino-1-{2,7-dichloro-9-[1-(4-chloro-phen...)
Affinity DataIC50:  380nMAssay Description:Inhibition of hERG by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM50109750(2-Dibutylamino-1-{2,7-dichloro-9-[1-(4-chloro-phen...)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibitory concentration against IKr potassium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed