BDBM50112349 CHEMBL3609328

SMILES CN1CCN(CC1)C1=Nc2cc(F)ccc2Nc2ccc(F)cc12

InChI Key InChIKey=PYSIAKZWZJNMNM-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50112349   

TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50112349(CHEMBL3609328)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant human muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50112349(CHEMBL3609328)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of wild type dephosphorylated form of PAK1 (249 to 545) (unknown origin) expressed in Escherichia coli using 5-Fluo-Ahx-AKRRRLSSLRA-COOH a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50112349(CHEMBL3609328)
Affinity DataIC50:  5.40E+4nMAssay Description:Inhibition of wild type phosphorylated form of PAK1 (249 to 545) (unknown origin) expressed in Escherichia coli using 5-Fluo-Ahx-AKRRRLSSLRA-COOH as ...More data for this Ligand-Target Pair
TargetHistamine H1 receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50112349(CHEMBL3609328)
Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant human histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed