BDBM50113458 CHEMBL3605975::US10800739, Compound (14)

SMILES NC(=O)c1cccc2CN(CCN3CCOCC3)C(=O)c12

InChI Key InChIKey=SDTLVPAVHMUAEM-UHFFFAOYSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50113458   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50113458(CHEMBL3605975 | US10800739, Compound (14))
Affinity DataKd:  160nMAssay Description:Binding affinity to full length recombinant human PARP-1 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM50113458(CHEMBL3605975 | US10800739, Compound (14))
Affinity DataKd:  580nMAssay Description:Preferably, for the screening method above cited, both the PARP protein and the 5H-phenanthridin-6-one-derived probe of formula (IP) are pre-mixed, o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50113458(CHEMBL3605975 | US10800739, Compound (14))
Affinity DataKd: <30nMAssay Description:Preferably, for the screening method above cited, both the PARP protein and the 5H-phenanthridin-6-one-derived probe of formula (IP) are pre-mixed, o...More data for this Ligand-Target Pair
In DepthDetails US Patent