BDBM50114048 CHEMBL3605410

SMILES Nc1cc(Br)ccc1C(=O)NC1(CCCCC1)C(=O)NCC#N

InChI Key InChIKey=KVQZUZVIKTWMTQ-UHFFFAOYSA-N

Data  2 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50114048   

TargetCathepsin K(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50114048(CHEMBL3605410)
Affinity DataKi:  10nMAssay Description:Inhibition of human cathepsin-K using Z-Gly-Pro-Arg-AMC as substrate preincubated for 30 mins measured after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetProcathepsin L(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50114048(CHEMBL3605410)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition of human cathepsin-L using Z-Phe-Arg-AMC as substrate preincubated for 30 mins measured after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed