BDBM50122979 3-Benzo[1,3]dioxol-5-yl-2-benzoyl-1,2,3,4-tetrahydro-pyrrolo[3,4-b]quinolin-9-one::CHEMBL344366

SMILES Oc1c2CN(C(c2nc2ccccc12)c1ccc2OCOc2c1)C(=O)c1ccccc1

InChI Key InChIKey=AFXANIIGPDJVPQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50122979   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50122979(3-Benzo[1,3]dioxol-5-yl-2-benzoyl-1,2,3,4-tetrahyd...)
Affinity DataKi:  2.5nMAssay Description:Inhibitory activity against Phosphodiesterase 5 (PDE5) was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50122979(3-Benzo[1,3]dioxol-5-yl-2-benzoyl-1,2,3,4-tetrahyd...)
Affinity DataKi:  2.5nMAssay Description:Inhibitory activity against human Phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed