BDBM50125832 (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid methyl ester::2-Hydroxy-4-oxo-4-phenyl-but-2-enoic acid methyl ester::CHEMBL16633::CHEMBL177429::CHEMBL456227

SMILES COC(=O)C(=O)CC(=O)c1ccccc1

InChI Key InChIKey=AQYAHPDSJAFBOS-UHFFFAOYSA-N

Data  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50125832   

TargetRNA-directed RNA polymerase(Hepatitis C virus)
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50125832((Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid meth...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity against Hepatitis C virus RNA dependent RNA polymerase nonstructural protein 5BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50125832((Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid meth...)
Affinity DataIC50: >3.33E+5nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolymerase acidic protein(Hepatitis C virus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125832((Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid meth...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of cap 1 ALMV primed Influenza transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolymerase acidic protein(Hepatitis C virus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125832((Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid meth...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibitory concentration against cap-dependent endonuclease activity of influenza virus RNPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolymerase acidic protein(Hepatitis C virus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125832((Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid meth...)
Affinity DataEC50: >2.50E+5nMAssay Description:Plaque growth inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50125832((Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid meth...)
Affinity DataIC50: >3.33E+5nMAssay Description:Inhibition of HIV1 integrase 3' processing activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed